When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum. ABSTRACT. We describe an unusual cluster of Corynebacterium striatum infections in 21 patients with chronic obstructive pulmonary disease (COPD) admitted. Objective: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. Methods: A.

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In phylogenetic trees based on concatenated protein sequences or 16S sttriatum, the genus Corynebacterium forms a distinct clade, within which is a distinct subclade, cluster I.

Twenty out of the 24 C. As with various species of a microbiota including their cousins in the genera Arcanobacterium and Trueperellathey usually are not pathogenic but can occasionally opportunistically capitalize on atypical access to tissues via wounds or weakened host defenses.

Gaiellales Rubrobacterales Thermoleophilales Solirubrobacterales. Corynebbacterium progressed to disseminated intravascular coagulation and disturbance of consciousness on day 67 of admission. Most species of corynebacteria are not lipophilic. They may also appear elliptical. Wikipedia articles needing page number citations from January CS1 Spanish-language sources es CS1 German-language sources de CS1 Portuguese-language sources pt Articles with ‘species’ microformats Articles containing Ancient Greek-language text All articles with unsourced statements Articles with unsourced statements from January CS1 maint: The cluster is made up of the species C.

Successful treatment of Corynebacterium striatum endocarditis with daptomycin plus rifampin. Corynebacterium striatum bacteremia associated with central venous catheter infection.

Case Reports in Infectious Diseases

Although an implantable cardioverter defibrillator CRT-D, Cardiac Resynchronization Therapy-Defibrillationwith biventricular pacing function, was replaced with PM for severe left ventricular functional decline, on day 12 of admission, an intra-aortic balloon pump IABP was also inserted because of multiple organ failure.


Although patients with implanted CRT-D may develop infectious endocarditis, obvious vegetation was never observed on echocardiography in these cases [ 11 ].

Please review our privacy policy. A variety of Gram-positive bacteria carry mobile mef genes. Although the biochemical properties of C. In conclusion, this study highlights the relevance of C. Wound infections due to opportunistic Corynebacterium species.

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The mef A-E gene was not found in any strain tested. Aminoglycosides are used as complementary antibiotics to treat serious infections caused by diphtheroids. The Microbial Production of Amino Acids. Microbiology and Molecular Biology Reviews.

Superti SV, et al.

The principal features of the genus Corynebacterium were described by Collins and Cummins in A spontaneous joint infection with Corynebacterium striatum.

To our knowledge, this is the second report which found both blood cultures and cultures from a central venous catheter tip positive for the same strain of C.

Among the 31 MDR isolates, 19 resistance profiles could be distinguished. In this study, we aimed to investigate the susceptibility of the 63 C.

Some asynergy in wall motion was detected by echocardiography, but no vegetation was seen. Susceptibility to aminoglycosides and distribution of aph and aac 3 -XI genes among Corynebacterium striatum clinical isolates. Gram-positive bacilli were detected in both blood culture samples; each set included aerobic and anaerobic cultures Figures 1 b and 1 c.

Notes Competing Interests The authors declare that they have no competing interests. Because her general condition worsened, implanted indwelling devices as central venous catheter might cause bacteremia by C. It is more common in developing countries [20] It can occasionally infect wounds, the vulvathe conjunctivaand the middle ear.


The gene erm B confers high-level resistance to macrolides in Campylobacter coli 33 and other relevant pathogens but is exceptional in Corynebacterium spp 31 Three of the conserved signature proteins have homologs found in the genus Dietziawhich is believed to be the closest related genus to Corynebacterium.

The high diversity of genotypes among the 63 C. Structure, Function, and Genetics. Journal of the American Podiatric Medical Association. This work highlights the high prevalence of multi-resistant strains and resistance genes among the C. Results Antimicrobial susceptibility testing and resistance profiles Fifty-nine The fact that many different antibiotic resistance profiles could be distinguished among the strains belonging to a particular PFGE pattern revealed that there was not a single strain but several closely related clones producing sporadic infections.

Abstract Corynebacterium striatum is a nosocomial opportunistic pathogen increasingly associated with a wide range of human infections and is often resistant to several antibiotics. They are widely distributed in nature in the microbiota of animals including the human microbiota and are mostly innocuous, most commonly existing in commensal relationships with their hosts. Effects of infection include granulomatous lymphadenopathypneumonitispharyngitisskin infections, and endocarditis.

Pathogenic species in other animals include C.

Corynebacterium striatum Bacteremia Associated with a Catheter-Related Blood Stream Infection

Letters in Applied Microbiology. In fourteen of the 21 fluoroquinolone-resistant C.

Ishiwada N, et al. Click on image for details. In Ford, Marvella E. Clonal multidrug-resistant Corynebacterium striatum strains, Italy.