Sclerosing adenosis (SA) is a benign proliferative condition of the terminal duct lobular units characterised by an increased number of acini and their glands. English Translation, Synonyms, Definitions and Usage Examples of Spanish Word ‘adenosis esclerosante mamaria’. el diagnóstico diferencial de lesiones benignas que simulan carcinoma, tales como hiperplasia cribiforme, adenosis esclerosante e hiperplasia adenomatosa .

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You can change the settings or obtain more information by clicking here. Unable to process the form. Images hosted on PathOut server: Sclerosing polycystic adenosis SPA is a rare, newly reported lesion of the salivary glands.

Images hosted on PathOut server: Breast – nonmalignant Adenosis Sclerosing adenosis Author: Home About Us Advertise Amazon. We report a case of sclerosing polycystic adenosis within the submandibular gland in a year-old woman.

Initially, it was asymptomatic and subsequently the patient developed light dysesthesias in the region. No nuclear atypia of the ductal and squamous epithelium was revealed Fig. Right to privacy and informed consent. Cytokeratin has been observed in the tubuloacinar elements and S, smooth muscle actin, and calponin stain is present in the myoepithelial cells.


Furthermore, there is evidence that monoclonal cell populations exist in some cases of SPA, however the meaning of this clonality is still uncertain. Reticulin stain, continuous basement membrane around glands.

What does sclerosing adenosis mean? Definition, meaning and sense

The authors declare that they have followed the protocols of their work center on the publication of patient data. The corresponding author is in possession of this document.

Si continua navegando, consideramos que acepta su uso. Sclerosing adenosis can appear as a focal or diffuse lesion. Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor HUMARA locus as a marker.

Hed Neck Pathol, 2pp.

Small ducts with microcalcifications. Fibroscopy was normal, whilst bimanual and cervical palpation noticed an enlarged, left submandibular gland, with a posterior adenopathy esvlerosante a mobile and rolling gland of about 2 cm in diameter. Multiple types of adenosis are described: Specific immunohistochemistry antibodies as anti-smooth muscle actin, can confirm the integrity of the myoepithelial cells layer in benign tumors, which is lost in carcinomatous lesions.

Pathology Outlines – Sclerosing adenosis

Travesera de Gracia,Barcelona, Barcelona, ES, maxilo elsevier. Pathol Res Pract,pp. Diagn Cytopathol, 38pp. Small bland ducts adjacent to nerve.


Conflict of esxlerosante The authors declare no conflict of interest.

Adenosis of the Breast

There is no gender predominance, although it is considered a slight predilection toward females. By comparison, the adjacent gland is not affected and presents no fibrosis, inflammatory infiltrates or atrophy. Thank you esclreosante updating your details.

A superficial parotidectomy was done and the microscopic study informed SPA. Br J Oral Maxillofac Surg. Discussion There have been about 51 cases of sclerosing polycyst adenosis SPA in the salivary glands published.

The treatment consists in excision of the tumor with a superficial parotidectomy, which has demonstrated high cure rates. The SPA is similar to the fibrocystic changes, sclerosing adenosis and adenoid tumors of the mammary gland.

However because of the risk of recurrence and the presence of cell clonality it has been considered that it might have a tumoral origin.